This text it is the exposition of arsenic (As) through residous of manganese (Mn) exploration developed by ICOMI. The avaliation of the physical emvironment in the study on the arsenic in the State of Amapá anticipated the sudy of human health once was necessary to know the sources and routes of exposition which could be reaching the human comunities. Among the several arsenic exposition ways, the consumption of water presents the greatest risc concerning the human health. Due to the divulgation of arsenic in the Industrial Area and anomalous grades in rivers. A work had been detailed on the water samples of the North Channel of the Amazon River from Santana, close to the sea analysing the arsenic and been repeated along of Pará River, from Breves Chanel to its mouth. The chemical affinity between manganese and arsenic is good and much better than affinity by the iron. The Serra do Navio oxide ore is a good example. The affinity has been a technique used and comercially in the equipments production for arsenic in removing water in order to become potable.